Caenorhabditis elegans brc-1 mutation increases the number of COSA-1 foci in him-8 and zim-2 mutants

Saito TT, Yamamoto K, Minami H, Tsujiue T. MicroPublication Biology 2024 Jul 25

GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans

Martinez-Garcia M, Naharro PR, Skinner MW, Baran KA, Lascarez-Lagunas LI, Nadarajan S, Shin N, Silva-García CG, Saito TT, Beese-Sims S, Diaz-Pacheco BN, Berson E, Castañer AB, Pacheco S, Martinez-Perez E, Jordan PW, Colaiácovo MP. PLoS Genetics 2023 Feb 21;19(2):e1010666. 

HIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis

Nadarajan S, Altendorfer E, Saito TT, Martinez-Garcia M, Colaiácovo MP. Proceedings of the National Academy of Sciences​ of the USA 2021 Apr 27;118(17):e2016363118.

The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline

Wang SY, Mao H, Shibuya H, Uzawa S, O'Brown ZK, Wesenberg S, Shin N, Saito TT, Gao J, Meyer BJ, Colaiácovo MP, Greer EL. PLoS Genetics 2019 Jul 8;15(7):e1008252. 

The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans

Li Q, Saito TT, Martinez-Garcia M, Deshong AJ, Nadarajan S, Lawrence KS, Checchi PM, Colaiacovo MP, Engebrecht J. PLoS Genetics 2018 Nov 1;14(11):e1007701. 

Regulation of Crossover Frequency and Distribution during Meiotic Recombination

Saito TT, Colaiácovo MP. Cold Spring Harbor Symposia on Quantitative Biology 2017;82:223-234. 

Crossover recombination mediated by HIM-18/SLX4-associated nucleases

Saito TT, Colaiácovo MP. Worm 2014 Mar 5;3:e28233. 

Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis

Saito TT, Lui DY, Kim HM, Meyer K, Colaiácovo MP. PLoS Genetics 2013;9(7):e1003586. 

SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline

Saito TT, Mohideen F, Meyer K, Harper JW, Colaiácovo MP. PLoS Genetics 2012 Aug;8(8):e1002888.

Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans

Schild-Prüfert K, Saito TT, Smolikov S, Gu Y, Hincapie M, Hill DE, Vidal M, McDonald K, Colaiácovo MP. Genetics 2011 Oct;189(2):411-21. 

Break to make a connection

Saito TT, Colaiácovo MP. PLoS Genetics 2011 Feb;7(2):e1002006. 

The Mek1 phosphorylation cascade plays a role in meiotic recombination of Schizosaccharomyces pombe

Tougan T, Kasama T, Ohtaka A, Okuzaki D, Saito TT, Russell P, Nojima H. Cell Cycle 2010 Dec 1;9(23):4688-702. 

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

Smogorzewska A, Desetty R, Saito TT, Schlabach M, Lach FP, Sowa ME, Clark AB, Kunkel TA, Harper JW, Colaiácovo MP, Elledge SJ. Molecular Cell 2010 Jul 9;39(1):36-47. 

Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates

Saito TT, Youds JL, Boulton SJ, Colaiácovo MP. PLoS Genetics 2009 Nov;5(11):e1000735.

Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe

Ohtaka A, Saito TT, Okuzaki D, Nojima H. Cell Division 2007 May 18;2:14. 

Mcp4, a meiotic coiled-coil protein, plays a role in F-actin positioning during Schizosaccharomyces pombe meiosis

Ohtaka A, Okuzaki D, Saito TT, Nojima H. Eukaryotic Cell 2007 Jun;6(6):971-83. 

Spo5/Mug12, a putative meiosis-specific RNA-binding protein, is essential for meiotic progression and forms Mei2 dot-like nuclear foci

Kasama T, Shigehisa A, Hirata A, Saito TT, Tougan T, Okuzaki D, Nojima H. Eukaryotic Cell 2006 Aug;5(8):1301-13. 

Mcp5, a meiotic cell cortex protein, is required for nuclear movement mediated by dynein and microtubules in fission yeast

Saito TT, Okuzaki D, Nojima H. Journal of Cell Biology 2006 Apr 10;173(1):27-33. 

Mcp6, a meiosis-specific coiled-coil protein of Schizosaccharomyces pombe, localizes to the spindle pole body and is required for horsetail movement and recombination

Saito TT, Tougan T, Okuzaki D, Kasama T, Nojima H. Journal of Cell Science 2005 Jan 15;118(Pt 2):447-59. 

Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination

Saito TT, Tougan T, Kasama T, Okuzaki D, Nojima H. Nucleic Acids Research 2004 Jun 21;32(11):3325-39.

Abundant poly(A)-bearing RNAs that lack open reading frames in Schizosaccharomyces pombe

Watanabe T, Miyashita K, Saito TT, Nabeshima K, Nojima H. DNA Research 2002 Dec 31;9(6):209-15. 

Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe

Watanabe T, Miyashita K, Saito TT, Yoneki T, Kakihara Y, Nabeshima K, Kishi YA, Shimoda C, Nojima H. Nucleic Acids Research 2001 Jun 1;29(11):2327-37.